SCHEMBL25682452

SCHEMBL25682452

Cn1c2ccc(C(C)(C)C)cc2c2c3sc4ccccc4c3ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.40
PGR P06401 2/20 0.38
RORA P35398 1/20 0.38
RORC P51449 1/20 0.38
RORB Q92753 1/20 0.38
NR1H3 Q13133 1/20 0.36
NPY5R Q15761 1/20 0.36
APEX1 P27695 1/20 0.36
TNKS O95271 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
KDM4E B2RXH2 4/20 0.35
MAPT P10636 4/20 0.35
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GPR3 P46089 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25682485 0.92 KIF11 (0.43) KIF11PGRRORARORCRORB
SCHEMBL25682428 0.91 KIF11 (0.42) KIF11PGRRORARORCRORB
SCHEMBL25682449 0.90 KIF11 (0.43) KIF11PGRRORARORCRORB
SCHEMBL25993491 0.86 KIF11 (0.39) KIF11PGRRORARORCRORB
SCHEMBL13183789 0.83 GPR3 (0.47) KIF11KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL25682739 0.83 KIF11 (0.39) KIF11PGRRORARORCRORB
SCHEMBL24728703 0.81 RXRA (0.40) TNKSTNKS2KDM4EMAPTL3MBTL1
SCHEMBL18566129 0.80 MAPT (0.38) KIF11TNKSTNKS2KDM4EMAPT
SCHEMBL25993498 0.80 KIF11 (0.42) KIF11PGRRORARORCRORB
SCHEMBL25682488 0.80 KIF11 (0.42) KIF11PGRRORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 US disclosed
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 US disclosed
EP-4190791-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT Kyulux, Inc. (JP) 2023-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CCNE2, CRY2 KIF11 2637/4885PGR 3110/4885RORA 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.