Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104182 | 0.79 | RIPK1 (0.44) | SMN1; SMN2MAPTTSHRALDH1A1HPGD | |
| SCHEMBL17801557 | 0.79 | TSHR (0.42) | HTTSMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL18907736 | 0.77 | SMN1; SMN2 (0.41) | HTTSMN1; SMN2MAPTTSHRATM | |
| SCHEMBL5821712 | 0.77 | SMN1; SMN2 (0.41) | HTTSMN1; SMN2MAPTTSHRATM | |
| SCHEMBL22893651 | 0.76 | MMP8 (0.42) | SMN1; SMN2GAAKMT2AMMP8 | |
| SCHEMBL10818200 | 0.76 | TSHR (0.46) | HTTSMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL26190499 | 0.74 | SMN1; SMN2 (0.38) | HTTSMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL18436940 | 0.74 | MMP8 (0.34) | MMP8 | |
| SCHEMBL19248359 | 0.73 | KDM4C (0.40) | SMN1; SMN2ALDH1A1GAAKMT2AMMP8 | |
| SCHEMBL9775242 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2MAPTALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3570972-B1 | METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES | OXFORD NANOPORE TECH LTD (GB) | 2021-08-18 | — | — | EP | disclosed |