SCHEMBL23764210

SCHEMBL23764210

CC1(C)C=CC=C(N(c2ccc(-c3cccnc3)cc2)c2ccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)cc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
PIK3CA P42336 1/20 0.32
PTGS2 P35354 1/20 0.31
PDK2 Q15119 1/20 0.30
USP1 O94782 1/20 0.30
WDR48 Q8TAF3 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
KIF11 P52732 1/20 0.30
MKNK1 Q9BUB5 1/20 0.30
MKNK2 Q9HBH9 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764213 0.87 CYP11B1 (0.31) CYP11B1
SCHEMBL23764223 0.85 KIF11 (0.37) CYP11B1CYP11B2KIF11MKNK1MKNK2
SCHEMBL23764211 0.83 MAPK11 (0.32)
SCHEMBL16484672 0.81 CYP11B1 (0.48) CYP11B1CYP11B2PIK3CAPTGS2PDK2
SCHEMBL16485349 0.81 CYP11B1 (0.48) CYP11B1CYP11B2PIK3CAPTGS2PDK2
SCHEMBL16485344 0.79 CYP11B1 (0.46) CYP11B1CYP11B2PIK3CAPTGS2USP1
SCHEMBL23764224 0.79 KMO (0.39) CYP11B1CYP11B2MKNK1MKNK2CYP2A6
SCHEMBL25619552 0.78 CYP11B1 (0.45) CYP11B1CYP11B2PIK3CAPTGS2PDK2
SCHEMBL23764209 0.76 CYP11B1 (0.34) CYP11B1CYP11B2USP1WDR48
SCHEMBL23764207 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed