SCHEMBL23764224

SCHEMBL23764224

CC1(C)C=CC=C(N(c2ccccc2)c2cccc(-c3cccnc3)c2)C=C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.39
EPHX2 P34913 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
FYN P06241 1/20 0.37
BACE1 P56817 8/20 0.36
MEN1 O00255 1/20 0.36
PSIP1 O75475 1/20 0.36
AXL P30530 1/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
CYP19A1 P11511 2/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
CYP17A1 P05093 1/20 0.35
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP2A6 P11509 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764223 0.91 KIF11 (0.37) MKNK1MKNK2CYP19A1CYP11B1CYP11B2
SCHEMBL23764221 0.88 NOTUM (0.36) PRMT6BACE1MKNK1CYP17A1CETP
SCHEMBL23764237 0.82 TGFBR1 (0.34) BACE1MAPTL3MBTL1CYP2A6CETP
SCHEMBL23764414 0.80
SCHEMBL23764225 0.79 NPC1 (0.36) CYP1A2
SCHEMBL23764210 0.79 CYP11B1 (0.35) MKNK1MKNK2CYP11B1CYP11B2CYP2A6
SCHEMBL23764229 0.78 MAPT (0.38) MAPT
SCHEMBL23764419 0.78 KCNA5 (0.33)
SCHEMBL16484501 0.77 CYP2A6 (0.54) KMOEPHX2PRMT6FYNBACE1
SCHEMBL23764418 0.75 ALDH1A1 (0.37) MEN1ALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed