SCHEMBL23766010

SCHEMBL23766010

CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAP1LC3B Q9GZQ8 8/20 0.47
▸ CRBN Q96SW2 11/20 0.47
▸ BRD4 O60885 2/20 0.47
▸ STAT3 P40763 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25756217 1.00 MAP1LC3B (0.47) MAP1LC3BCRBNBRD4STAT3
SCHEMBL23766083 0.99 MAP1LC3B (0.47) MAP1LC3BCRBNBRD4STAT3
SCHEMBL23766141 0.97 MAP1LC3B (0.47) MAP1LC3BCRBNBRD4STAT3
SCHEMBL24068351 0.97 MAP1LC3B (0.46) MAP1LC3BCRBNBRD4STAT3
SCHEMBL25755912 0.97 MAP1LC3B (0.47) MAP1LC3BCRBNBRD4STAT3
SCHEMBL23765987 0.96 MAP1LC3B (0.47) MAP1LC3BCRBNBRD4STAT3
SCHEMBL24068374 0.96 MAP1LC3B (0.46) MAP1LC3BCRBNBRD4STAT3
SCHEMBL24068376 0.95 MAP1LC3B (0.45) MAP1LC3BCRBNBRD4STAT3
SCHEMBL23765744 0.95 MAP1LC3B (0.46) MAP1LC3BCRBNBRD4STAT3
SCHEMBL23766089 0.95 CRBN (0.47) MAP1LC3BCRBNBRD4STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369853-A1 TARGETED PROTEASE DEGRADATION PLATFORM EUBULUS BIOTHERAPEUTICS INC. (CN) 2021-12-02 — — US disclosed
EP-3865152-A1 TARGETED PROTEASE DEGRADATION PLATFORM Eubulus Biotherapeutics Inc. (CN) 2021-08-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369853-A1 TARGETED PROTEASE DEGRADATION PLATFORM PSMB1, MDM2, XIAP MAP1LC3B 730/4885CRBN 284/4885BRD4 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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