SCHEMBL23766089

SCHEMBL23766089

CC(C)(C)OC(=O)N(CCOCCN=[N+]=[N-])CCOCCOCCOCC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.47
▸ RIPK2 O43353 1/20 0.47
▸ MAP1LC3B Q9GZQ8 6/20 0.47
▸ BRD4 O60885 4/20 0.47
▸ STAT3 P40763 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23765893 1.00 CRBN (0.47) CRBNRIPK2MAP1LC3BBRD4STAT3
SCHEMBL23765755 0.97 CRBN (0.47) CRBNRIPK2MAP1LC3BBRD4STAT3
SCHEMBL25756369 0.96 CRBN (0.47) CRBNRIPK2MAP1LC3BBRD4
SCHEMBL23766010 0.95 MAP1LC3B (0.47) CRBNMAP1LC3BBRD4STAT3
SCHEMBL25756217 0.95 MAP1LC3B (0.47) CRBNMAP1LC3BBRD4STAT3
SCHEMBL23766141 0.95 MAP1LC3B (0.47) CRBNMAP1LC3BBRD4STAT3
SCHEMBL24068351 0.94 MAP1LC3B (0.46) CRBNMAP1LC3BBRD4STAT3
SCHEMBL23766083 0.94 MAP1LC3B (0.47) CRBNMAP1LC3BBRD4STAT3
SCHEMBL24068867 0.94 MAP1LC3B (0.47) CRBNRIPK2MAP1LC3BBRD4STAT3
SCHEMBL25755912 0.94 MAP1LC3B (0.47) CRBNMAP1LC3BBRD4STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369853-A1 TARGETED PROTEASE DEGRADATION PLATFORM EUBULUS BIOTHERAPEUTICS INC. (CN) 2021-12-02 — — US disclosed
EP-3865152-A1 TARGETED PROTEASE DEGRADATION PLATFORM Eubulus Biotherapeutics Inc. (CN) 2021-08-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369853-A1 TARGETED PROTEASE DEGRADATION PLATFORM PSMB1, MDM2, XIAP CRBN 284/4885RIPK2 776/4885MAP1LC3B 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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