Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 1/20 | 0.50 |
| ▸ | ADH4 | P08319 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680185 | 1.00 | ADH1C (0.50) | ADH1CADH1AADH4DNM1KDM4E | |
| SCHEMBL11569526 | 0.98 | ADH1C (0.53) | ADH1CADH1AADH4DNM1KDM4E | |
| SCHEMBL1678954 | 0.98 | ADH1C (0.53) | ADH1CADH1AADH4DNM1KDM4E | |
| SCHEMBL11570725 | 0.98 | ADH1C (0.53) | ADH1CADH1AADH4DNM1KDM4E | |
| SCHEMBL24437737 | 0.93 | DNM1 (0.44) | ADH1CADH1AADH4DNM1KDM4E | |
| SCHEMBL1678797 | 0.92 | — | — | |
| SCHEMBL17351084 | 0.91 | DNM1 (0.48) | ADH1CADH1AADH4DNM1GBA1 | |
| SCHEMBL14546899 | 0.91 | ADH1A (0.42) | ADH1CADH1AADH4DNM1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7433084 | 0.90 | ADH1C (0.41) | ADH1CADH1AADH4DNM1KDM4E | |
| SCHEMBL23221024 | 0.89 | ADH1C (0.43) | ADH1CADH1AADH4DNM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163339-A1 | CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS | GENEVANT SCIENCES GMBH (US) | 2021-08-19 | — | — | WO | disclosed |