Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21318015 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL10655685 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL1706638 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL23754120 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL23768068 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL9129292 | 0.80 | CA12 (0.61) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL322149 | 0.79 | CA12 (0.69) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL28451530 | 0.77 | CA12 (0.67) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10254012 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL1706924 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146180-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| WO-2021160680-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146180-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | DDT, ACHE, PNMT | KDM4E 2283/4885ALDH1A1 1080/4885MAPT 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.