Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983697 | 0.88 | CFTR (0.51) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL23754415 | 0.82 | CFTR (0.61) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL2242947 | 0.82 | CFTR (0.57) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL15797323 | 0.82 | CFTR (0.61) | CFTRNOTUMTSHRMAPTGAA | |
| SCHEMBL1763845 | 0.81 | CFTR (0.49) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL167743 | 0.80 | CFTR (0.48) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL19491469 | 0.80 | CFTR (0.48) | CFTRNOTUMMAPTSOS1HPGD | |
| SCHEMBL22400474 | 0.79 | CFTR (0.61) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL8037239 | 0.79 | CFTR (0.47) | CFTRNOTUMCA12CA1CA2 | |
| SCHEMBL29528849 | 0.79 | CFTR (0.61) | CFTRNOTUMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146180-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| WO-2021160680-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146180-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | DDT, ACHE, PNMT | CFTR 2696/4885NOTUM 372/4885CA12 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.