Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016504 | 0.88 | ALDH1A1 (0.35) | ALDH1A1BLML3MBTL1 | |
| SCHEMBL21016699 | 0.86 | ALDH1A1 (0.33) | ALDH1A1BLML3MBTL1 | |
| SCHEMBL21016503 | 0.83 | MEN1 (0.33) | ALDH1A1BLML3MBTL1 | |
| SCHEMBL23768193 | 0.78 | PKM (0.31) | — | |
| SCHEMBL16840699 | 0.74 | CYP1A2 (0.38) | ALDH1A1BLML3MBTL1 | |
| SCHEMBL5889042 | 0.69 | AAK1 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL25986789 | 0.68 | HRH4 (0.34) | ALDH1A1BLML3MBTL1 | |
| SCHEMBL5889118 | 0.68 | L3MBTL1 (0.44) | ALDH1A1BLML3MBTL1 | |
| SCHEMBL19530469 | 0.67 | KDM4E (0.35) | — | |
| SCHEMBL16841158 | 0.64 | PKM (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253554-A1 | SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253554-A1 | SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS | TYK2, JAK3, JAK2 | ALDH1A1 4424/4885BLM 3427/4885L3MBTL1 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.