Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 8/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165295 | 0.80 | MAOA (0.54) | MAOBMAOAPRKCIAKR1B1MIF | |
| SCHEMBL2223886 | 0.76 | KDM4E (0.58) | MAOBMAOAPRKCIAKR1B1MIF | |
| SCHEMBL3825921 | 0.76 | MAOA (0.92) | MAOBMAOAPRKCIAKR1B1MIF | |
| SCHEMBL9119395 | 0.72 | MAOA (0.43) | MAOBMAOAPRKCIESR1ESR2 | |
| SCHEMBL30917292 | 0.72 | MAOA (0.39) | MAOBMAOAPRKCIPBRM1 | |
| SCHEMBL7493611 | 0.72 | MAOA (0.39) | MAOBMAOAPRKCIPBRM1 | |
| SCHEMBL228128 | 0.72 | MAOA (1.00) | MAOBMAOAPRKCIAKR1B1MIF | |
| SCHEMBL27323917 | 0.71 | MAOB (0.77) | MAOBMAOAPRKCIAKR1B1MIF | |
| SCHEMBL20165279 | 0.70 | VHL (0.51) | MAOBMAOAPRKCIHSD17B1ESR1 | |
| SCHEMBL2312578 | 0.69 | AKR1B1 (0.58) | MAOBMAOAPRKCIAKR1B1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210255191-A1 | FLUORESCENT DYE AND USE THEREOF | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-08-19 | — | — | US | disclosed |