SCHEMBL27323917 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MAOB	P27338	9/20	0.77

▸	MAOA	P21397	8/20	0.77

▸	PRKCI	P41743	1/20	0.77

▸	HSD17B1	P14061	2/20	0.58

▸	PBRM1	Q86U86	1/20	0.55

▸	AKR1B1	P15121	2/20	0.45

▸	CYP26A1	O43174	2/20	0.44

▸	ESR1	P03372	1/20	0.44

▸	UGT1A1	P22309	1/20	0.44

▸	ESR2	Q92731	1/20	0.44

▸	MIF	P14174	3/20	0.43

▸	BAZ2B	Q9UIF8	1/20	0.43

▸	GRM5	P41594	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3825921	0.91	MAOA (0.92)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL228128	0.87	MAOA (1.00)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL5145478	0.83	PBRM1 (0.78)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL29983572	0.79	PBRM1 (0.78)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL385554	0.79	PBRM1 (0.78)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL389710	0.79	MAOB (0.78)	MAOBMAOAPRKCIHSD17B1PBRM1
Hydrochloric Acid SCHEMBL6531236	0.76	PBRM1 (0.72)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL784291	0.76	MAOB (0.59)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL4090561	0.74	HSD17B1 (1.00)	MAOBMAOAPRKCIHSD17B1PBRM1
SCHEMBL7245439	0.72	MAOA (0.55)	MAOBMAOAPRKCIPBRM1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024025953-A2	THERAPEUTIC USES OF UROLITHIN DERIVATIVES	VANDRIA SA (CH)	2024-02-01	—	—	WO	disclosed