SCHEMBL23769050

SCHEMBL23769050

O=C(Nc1ccc2c(c1)N(c1ccccc1)CCS2)Nc1ccc2cc[nH]c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.41
ESR1 P03372 5/20 0.40
PYGL P06737 1/20 0.40
CFTR P13569 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRA6 Q16445 1/20 0.40
MAOA P21397 1/20 0.40
IDH1 O75874 1/20 0.40
NOTUM Q6P988 1/20 0.39
MAPT P10636 5/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29979338 1.00 FAAH (0.41) FAAHESR1PYGLCFTRGABRA1
SCHEMBL29978704 0.94 ESR1 (0.40) FAAHESR1PYGLCFTRGABRA1
SCHEMBL23768831 0.94 ESR1 (0.40) FAAHESR1PYGLCFTRGABRA1
SCHEMBL30248570 0.89 FAAH (0.44) FAAHMAPTNPC1RAB9AKDM4E
SCHEMBL25028038 0.89 FAAH (0.44) FAAHMAPTNPC1RAB9AKDM4E
SCHEMBL25028041 0.85 ROCK2 (0.44) FAAHCFTRGABRA1GABRB1GABRA5
SCHEMBL30895162 0.85 ROCK2 (0.44) FAAHCFTRGABRA1GABRB1GABRA5
SCHEMBL23768826 0.84 MAPT (0.42) FAAHESR1MAPTNPC1RAB9A
SCHEMBL29978634 0.84 MAPT (0.42) FAAHESR1MAPTNPC1RAB9A
SCHEMBL23769036 0.83 MAPT (0.56) MAPTALDH1A1KDM4EHTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151304-A Small molecule interferon gene stimulating factor (STING) antagonists 库拉德夫制药私人有限公司 2022-10-04 CN claimed
US-20230124361-A1 SMALL MOLECULE STING ANTAGONISTS CURADEV PHARMA PVT. LTD. (IN) 2023-04-20 US disclosed
WO-2021161230-A1 SMALL MOLECULE STING ANTAGONISTS CURADEV PHARMA PVT. LTD. (IN) 2021-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230124361-A1 SMALL MOLECULE STING ANTAGONISTS STING1, CGAS, MAVS FAAH 1546/4885ESR1 4033/4885PYGL 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.