SCHEMBL23769110

SCHEMBL23769110

CC(C)(C)OC(=O)Nc1ccc2c(c1)N(Cc1ccccc1)CCS2

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.59
SMN1; SMN2 Q16637 6/20 0.53
TP53 P04637 3/20 0.53
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 3/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
GFER P55789 1/20 0.51
THRB P10828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30191291 0.81 ALDH1A1 (0.51) MAPTSMN1; SMN2TP53ALDH1A1MEN1
SCHEMBL23769013 0.81 ALDH1A1 (0.51) MAPTSMN1; SMN2TP53ALDH1A1MEN1
SCHEMBL23769051 0.79 MAPT (0.64) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL29978899 0.79 MAPT (0.64) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL29226906 0.79 MAPT (0.59) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL21905570 0.76 MAPT (0.68) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL23769036 0.75 MAPT (0.56) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL29978853 0.75 MAPT (0.56) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL23769038 0.74 MAPT (0.74) MAPTSMN1; SMN2TP53KDM4EALDH1A1
SCHEMBL18144419 0.74 RORC (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151304-B Small molecule interferon gene stimulating factor (STING) antagonists 库拉德夫制药私人有限公司 2025-02-11 CN disclosed
US-20230124361-A1 SMALL MOLECULE STING ANTAGONISTS CURADEV PHARMA PVT. LTD. (IN) 2023-04-20 US disclosed
US-20230124361-A1 SMALL MOLECULE STING ANTAGONISTS CURADEV PHARMA PVT. LTD. (IN) 2023-04-20 US disclosed
CN-115151304-A Small molecule interferon gene stimulating factor (STING) antagonists 库拉德夫制药私人有限公司 2022-10-04 CN disclosed
WO-2021161230-A1 SMALL MOLECULE STING ANTAGONISTS CURADEV PHARMA PVT. LTD. (IN) 2021-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230124361-A1 SMALL MOLECULE STING ANTAGONISTS STING1, CGAS, MAVS MAPT 3716/4885SMN1; SMN2 1579/4885TP53 3011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.