SCHEMBL23770276

SCHEMBL23770276

c1ccc(-c2ccc(-c3cccc(N(c4ccccc4-c4ccc5oc6ccccc6c5c4)c4cccc5c4-c4ccccc4C5(c4ccccc4)c4ccccc4)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
PLA2G10 O15496 1/20 0.32
ALOX5 P09917 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23770278 0.98 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL23770244 0.95 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL23770277 0.95 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10ALOX5HSP90AA1
SCHEMBL23233478 0.95 CA12 (0.31) PLA2G2APLA2G4A
SCHEMBL23770111 0.94 MMP12 (0.32) ALOX5
SCHEMBL23770203 0.94 PLA2G2A (0.31) PLA2G2APLA2G4AALOX5HSP90AA1HSP90AB1
SCHEMBL23770202 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10ALOX5HSP90AA1
SCHEMBL23770252 0.94 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10ALOX5HSP90AA1
SCHEMBL17855017 0.94 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10ALOX5HSP90AA1
SCHEMBL23770148 0.94 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210253546-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253546-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE RER1, ESR1, RFT1 PLA2G2A 3655/4885PLA2G4A 4192/4885PLA2G10 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.