Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970107 | 1.00 | MGLL (0.33) | MGLLDGAT1KCNH2CACNA1GCACNA1H | |
| SCHEMBL23770639 | 0.91 | MGLL (0.35) | MGLLKCNH2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL19970136 | 0.90 | BTK (0.33) | — | |
| SCHEMBL19970145 | 0.90 | BTK (0.33) | — | |
| SCHEMBL23770821 | 0.87 | DGAT1 (0.33) | DGAT1KCNH2 | |
| SCHEMBL23770636 | 0.86 | DGAT1 (0.33) | DGAT1KCNH2 | |
| SCHEMBL19970115 | 0.86 | DGAT1 (0.34) | DGAT1KCNH2 | |
| SCHEMBL22338250 | 0.86 | DGAT1 (0.36) | DGAT1KCNH2 | |
| SCHEMBL19927725 | 0.85 | MGLL (0.32) | MGLLDGAT1KCNH2CACNA1GCACNA1H | |
| SCHEMBL19927728 | 0.85 | MGLL (0.32) | MGLLDGAT1KCNH2CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |