Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770487 | 0.91 | MGLL (0.33) | MGLLCACNA1GCACNA1HCACNA1IPTGER1 | |
| SCHEMBL19970107 | 0.91 | MGLL (0.33) | MGLLCACNA1GCACNA1HCACNA1IPTGER1 | |
| SCHEMBL23770871 | 0.86 | MEN1 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19951384 | 0.84 | MGLL (0.35) | MGLLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23770500 | 0.83 | RORC (0.32) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23770499 | 0.82 | PTPN11 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23770868 | 0.81 | PTPN11 (0.37) | CNR1PTPN11KCNH2 | |
| SCHEMBL23770884 | 0.81 | RORC (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19970136 | 0.81 | BTK (0.33) | — | |
| SCHEMBL19970145 | 0.81 | BTK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |