Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770715 | 0.91 | AGPAT2 (0.34) | SCN10AMAPK14HSD11B1CCNT1 | |
| SCHEMBL23770558 | 0.88 | AGPAT2 (0.40) | MAPK14 | |
| SCHEMBL23770414 | 0.87 | ALOX5AP (0.34) | CCNT1CDK9 | |
| SCHEMBL23770637 | 0.85 | PDE4B (0.38) | CCNT1CDK9 | |
| SCHEMBL23770412 | 0.85 | CCNT1 (0.34) | CCNT1CDK9 | |
| SCHEMBL23770409 | 0.84 | BACE1 (0.35) | DPP4SCN10ATP53 | |
| SCHEMBL23770415 | 0.84 | ADORA2A (0.34) | DPP4TP53 | |
| SCHEMBL23770434 | 0.83 | — | — | |
| SCHEMBL23770546 | 0.82 | — | — | |
| SCHEMBL23770432 | 0.81 | SCN9A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |