Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770590 | 0.90 | ADORA2A (0.35) | BACE1EPHA4HSP90AA1DPP4DCUN1D1 | |
| SCHEMBL23770633 | 0.89 | PLA2G7 (0.36) | BACE1MYCWDR5EPHA4HSP90AA1 | |
| SCHEMBL23770415 | 0.89 | ADORA2A (0.34) | BACE1DPP4GAATP53 | |
| SCHEMBL23770545 | 0.86 | DHFR (0.30) | — | |
| SCHEMBL23770605 | 0.86 | — | — | |
| SCHEMBL23770555 | 0.86 | ADORA2A (0.32) | MYCWDR5KDM4EALDH1A1KMT2A | |
| SCHEMBL23770769 | 0.86 | ALDH1A1 (0.38) | HSP90AA1DPP4HSP90AB1DCUN1D1KDM4E | |
| SCHEMBL23770569 | 0.86 | EPAS1 (0.34) | BACE1MYCWDR5KDM4E | |
| SCHEMBL23770624 | 0.86 | — | — | |
| SCHEMBL23770756 | 0.86 | BACE1 (0.36) | BACE1DPP4SCN9AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |