Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770854 | 0.98 | DGAT1 (0.33) | DGAT1KCNH2CCNT1CDK9RORC | |
| SCHEMBL19970138 | 0.98 | DGAT1 (0.33) | DGAT1KCNH2CCNT1CDK9RORC | |
| SCHEMBL23770655 | 0.91 | DGAT1 (0.32) | DGAT1KCNH2RORC | |
| SCHEMBL23770490 | 0.89 | DGAT1 (0.30) | DGAT1KCNH2RORC | |
| SCHEMBL19970115 | 0.89 | DGAT1 (0.34) | DGAT1KCNH2 | |
| SCHEMBL22338250 | 0.89 | DGAT1 (0.36) | DGAT1KCNH2 | |
| SCHEMBL19970080 | 0.89 | RBP4 (0.35) | — | |
| SCHEMBL19970104 | 0.89 | RBP4 (0.35) | — | |
| SCHEMBL19970213 | 0.89 | RBP4 (0.35) | — | |
| SCHEMBL23770500 | 0.88 | RORC (0.32) | CCNT1CDK9RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |