Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970084 | 0.91 | BTK (0.33) | EPHX2 | |
| SCHEMBL19970085 | 0.91 | BTK (0.33) | EPHX2 | |
| SCHEMBL23770746 | 0.88 | RORC (0.33) | RORCGPBAR1PRKCAPRKCQCYP2C9 | |
| SCHEMBL23770654 | 0.88 | RORC (0.40) | RORCGPBAR1 | |
| SCHEMBL23770709 | 0.86 | AURKA (0.32) | CYP2C9EPHX2CACNA1CSCN5A | |
| SCHEMBL19970208 | 0.86 | BTK (0.34) | EPHX2 | |
| SCHEMBL19970137 | 0.86 | BTK (0.34) | EPHX2 | |
| SCHEMBL23770891 | 0.85 | BTK (0.33) | PRKCAPRKCQEPHX2 | |
| SCHEMBL23770801 | 0.85 | GPBAR1 (0.33) | RORCGPBAR1PRKCAPRKCQ | |
| SCHEMBL23770721 | 0.85 | GPBAR1 (0.33) | RORCGPBAR1PRKCAPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |