Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770750 | 0.92 | DGAT1 (0.32) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL23770738 | 0.90 | SSTR5 (0.33) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL19970115 | 0.90 | DGAT1 (0.34) | DGAT1KCNH2HCRTR1HCRTR2CNR1 | |
| SCHEMBL23770774 | 0.88 | PTGES (0.31) | DGAT1KCNH2 | |
| SCHEMBL23770490 | 0.83 | DGAT1 (0.30) | DGAT1KCNH2 | |
| SCHEMBL19925808 | 0.83 | CTSA (0.34) | CTSACYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL19925805 | 0.83 | CTSA (0.34) | CTSACYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL29464511 | 0.83 | CTSA (0.34) | CTSACYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL19970116 | 0.83 | DGAT1 (0.35) | DGAT1KCNH2CNR1 | |
| SCHEMBL23770832 | 0.82 | RBP4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |