SCHEMBL237757

SCHEMBL237757

Cc1cc(C(C)Cc2cccc(CC(C)c3cc(C)c(O)c(C)c3)c2)cc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.43
ESR2 Q92731 1/20 0.43
ALDH1A1 P00352 3/20 0.40
PTGS2 P35354 5/20 0.38
PTGS1 P23219 4/20 0.38
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
PNMT P11086 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
ALOX15 P16050 3/20 0.35
ALOX12 P18054 3/20 0.35
SLC6A2 P23975 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
TP53 P04637 2/20 0.35
CYP3A4 P08684 2/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 2/20 0.35
RECQL P46063 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19478611 0.90 PTGS1 (0.41) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL8661885 0.89 ESR1 (0.47) ESR1ESR2PTGS2PTGS1SLC6A2
SCHEMBL1581241 0.85 ESR1 (0.44) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL5137345 0.83 ESR1 (0.52) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL697803 0.83 ESR1 (0.44) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL582053 0.81 ESR1 (0.42) ESR1ESR2ALDH1A1PTGS2GABRA1
SCHEMBL19478530 0.81 GABRA1 (0.39) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL2554988 0.80 GABRA1 (0.42) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL15051454 0.79 ESR1 (0.57) ESR1ESR2ALDH1A1PTGS2PTGS1
SCHEMBL28161123 0.79 ESR1 (0.47) ESR1ESR2PTGS2PTGS1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 733 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599706-A Method for producing polyester carbonates 科思创知识产权两合公司 2022-06-07 CN claimed
EP-2286898-B1 Method for making polycarbonate BAYER IP GMBH (DE) 2015-09-23 EP claimed
EP-2096131-B1 Method for making polycarbonate BAYER IP GMBH (DE) 2015-01-28 EP claimed
US-8106144-B2 Process for producing polycarbonate BAYER MATERIALSCIENCE AG (DE) 2012-01-31 US claimed
EP-2090605-B1 Method for making polycarbonates BAYER MATERIALSCIENCE AG (DE) 2011-07-13 EP claimed
EP-2286898-A1 Method for making polycarbonate Bayer MaterialScience AG (DE) 2011-02-23 EP claimed
US-7863403-B2 Process for the preparation of polycarbonates and diaryl carbonate BAYER MATERIALSCIENCE AG (DE) 2011-01-04 US claimed
US-20100324256-A1 PROCESS FOR PRODUCING POLYCARBONATE BAYER MATERIALSSCIENCE AG (DE) 2010-12-23 US claimed
US-20090240021-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATES AND DIARYL CARBONATE BAYER MATERIALSCIENCE AG (DE) 2009-09-24 US claimed
EP-2096131-A1 Method for making polycarbonate Bayer MaterialScience AG (DE) 2009-09-02 EP claimed
US-20090215977-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BAYER MATERIALSCIENCE AG (DE) 2009-08-27 US claimed
EP-2090605-A1 Method for making polycarbonates Bayer MaterialScience AG (DE) 2009-08-19 EP claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
WO-2026099070-A2 BLENDS OF THERMOPLASTIC POLYMERS WITH COVALENT ADAPTABLE NETWORKS COVESTRO DEUTSCHLAND AG (DE) 2026-05-15 WO disclosed
US-20260132242-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2026-05-14 US disclosed
US-20020035234-A1 Continuous preparation of polycarbonate GENERAL ELECTRIC COMPANY 2002-03-21 US disclosed
WO-2002008311-A2 CONTINUOUS PREPARATION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-01-31 WO disclosed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132242-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT ASH2L, ARL1, CARM1 ESR1 2826/4885ESR2 1296/4885ALDH1A1 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.