Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324546 | 0.85 | ESR1 (0.42) | ESR1ESR2GABRA1GABRB2CRHBP | |
| SCHEMBL237757 | 0.81 | ESR1 (0.43) | ESR1ESR2GABRA1GABRB2CYP2C19 | |
| SCHEMBL27981343 | 0.78 | ADRB2 (0.38) | ESR1ESR2CYP3A4TDP1TSHR | |
| SCHEMBL1956103 | 0.78 | ADRB2 (0.38) | ESR1ESR2CYP3A4TDP1TSHR | |
| SCHEMBL901082 | 0.78 | ADRB2 (0.38) | ESR1ESR2CYP3A4TDP1TSHR | |
| SCHEMBL144607 | 0.77 | ESR1 (0.71) | ESR1ESR2CYP2C19PNMTCYP3A4 | |
| SCHEMBL27981742 | 0.74 | PTPN1 (0.41) | ESR1ESR2CYP2C19TSHRHIF1A | |
| SCHEMBL901085 | 0.74 | PTPN1 (0.41) | ESR1ESR2CYP2C19TSHRHIF1A | |
| SCHEMBL3175987 | 0.74 | KDM4E (0.52) | ESR1ESR2CYP2C19CYP3A4TDP1 | |
| SCHEMBL3684825 | 0.74 | TAAR1 (0.50) | ESR1ESR2SLC6A2SLC6A3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | claimed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | claimed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | claimed |
| EP-1307499-B2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1307499-B1 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | disclosed |
| US-6562937-B2 | Endcapping with phenol | GENERAL ELECTRIC COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | disclosed |
| US-20020035234-A1 | Continuous preparation of polycarbonate | GENERAL ELECTRIC COMPANY | 2002-03-21 | — | — | US | disclosed |