Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15655345 | 0.91 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4ATMTDP1 | |
| SCHEMBL27148409 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNANAAA | |
| SCHEMBL25212053 | 0.86 | DGKA (0.44) | ALDH1A1TSHRCYP3A4ATMTDP1 | |
| SCHEMBL27388377 | 0.85 | NAAA (0.35) | ALDH1A1SLC1A3SLC1A2SLC1A1NAAA | |
| SCHEMBL28788296 | 0.85 | NAAA (0.35) | ALDH1A1SLC1A3SLC1A2SLC1A1NAAA | |
| SCHEMBL28197402 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4ATMTDP1 | |
| SCHEMBL13324439 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5755476 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4ATMTDP1 | |
| SCHEMBL11332071 | 0.82 | CYP1A2 (0.55) | ALDH1A1TSHRCYP3A4ATMTDP1 | |
| SCHEMBL10522310 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873938-A1 | DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS | Novartis AG (CH) | 2021-09-08 | — | — | EP | disclosed |