Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779004 | 0.83 | HRH3 (0.42) | — | |
| SCHEMBL28475381 | 0.75 | GRM5 (0.36) | CREBBP | |
| SCHEMBL22831718 | 0.72 | NR1H2 (0.39) | — | |
| SCHEMBL28558608 | 0.72 | CREBBP (0.34) | CREBBP | |
| Hydrochloric Acid SCHEMBL23778900 | 0.72 | HRH3 (0.32) | — | |
| SCHEMBL17925617 | 0.69 | CREBBP (0.34) | CREBBP | |
| SCHEMBL20596105 | 0.69 | CREBBP (0.34) | CREBBP | |
| SCHEMBL23705926 | 0.67 | DRD2 (0.39) | CREBBP | |
| SCHEMBL23705880 | 0.66 | CREBBP (0.34) | CREBBP | |
| SCHEMBL22831722 | 0.66 | HRH4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873909-A1 | NOVEL 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AiCuris GmbH & Co. KG (DE) | 2021-09-08 | — | — | EP | disclosed |