Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 13/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22831716 | 0.85 | NR1H2 (0.40) | GRM5 | |
| SCHEMBL22831725 | 0.78 | HRH4 (0.46) | — | |
| SCHEMBL22854156 | 0.78 | DRD2 (0.41) | GRM5 | |
| SCHEMBL22854165 | 0.77 | OPRM1 (0.34) | GRM5 | |
| SCHEMBL22854231 | 0.77 | HRH4 (0.49) | — | |
| SCHEMBL22854158 | 0.77 | HRH4 (0.48) | — | |
| SCHEMBL22854166 | 0.77 | DRD2 (0.40) | — | |
| SCHEMBL22854139 | 0.77 | HRH4 (0.49) | — | |
| SCHEMBL23778976 | 0.75 | ITGB3 (0.32) | CREBBP | |
| SCHEMBL22831723 | 0.75 | GRM5 (0.38) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801331-A | Indole-2-carbonyl compounds and their use for the treatment of hepatitis b | 诺华股份有限公司 | 2020-10-20 | — | — | CN | disclosed |