Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | TET3 | O43151 | 3/20 | 0.69 |
| ▸ | FBXL19 | Q6PCT2 | 3/20 | 0.69 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.69 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.69 |
| ▸ | CXXC4 | Q9H2H0 | 3/20 | 0.69 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.69 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.69 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636624 | 0.86 | CA12 (0.59) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL5172596 | 0.86 | KMT2A (0.53) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL27381366 | 0.86 | KMT2A (0.65) | KMT2ATET3FBXL19CXXC5KDM2B | |
| Hydrochloric Acid SCHEMBL8635061 | 0.84 | KMT2A (0.63) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3790649 | 0.84 | KMT2A (0.51) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3931269 | 0.84 | KMT2A (0.71) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3441871 | 0.82 | ALDH1A1 (0.54) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL6391 | 0.82 | AKR1C1 (0.83) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL31016196 | 0.82 | AKR1C1 (0.83) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL1309812 | 0.82 | SLC18A3 (0.60) | KMT2ATET3FBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873600-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2021-09-08 | — | — | EP | disclosed |
| CN-101128435-A | Pyrazolone compounds as metabotropic glutamate receptor agonists for the treatment of neurological and psychiatric disorders | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |