SCHEMBL23780587

SCHEMBL23780587

COn1cccc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MCL1 Q07820 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23780597 0.82 LMNA (0.40) POLBTDP1L3MBTL1CA1CA2
SCHEMBL23798600 0.80 TDP1 (0.40) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL14245493 0.80 POLB (0.37) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL23780595 0.79 TDP1 (0.39) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL23780602 0.79 L3MBTL1 (0.39) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL6832383 0.76 LMNA (0.40) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL5512362 0.76 GAA (0.38) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL5510858 0.75 POLB (0.39) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL23780589 0.73 TSHR (0.41) TDP1L3MBTL1TSHRALDH1A1MEN1
SCHEMBL23798638 0.72 TSHR (0.43) TDP1TSHRALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI POLB 2041/4885APEX1 3616/4885TDP1 4847/4885
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI POLB 2041/4885APEX1 3616/4885TDP1 4847/4885
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI POLB 2041/4885APEX1 3616/4885TDP1 4847/4885
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI POLB 2041/4885APEX1 3616/4885TDP1 4847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.