SCHEMBL23780592

SCHEMBL23780592

N#Cc1cccn1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
MAOB P27338 2/20 0.42
CTSL P07711 2/20 0.38
CTSB P07858 2/20 0.38
CTSK P43235 2/20 0.38
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.37
CYP1A2 P05177 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
KMT2A Q03164 2/20 0.35
IDO1 P14902 1/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
ATP4A P20648 1/20 0.35
MAPK1 P28482 1/20 0.35
ATP4B P51164 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11707767 0.79 IDO1 (0.45) SMN1; SMN2MAOBKMT2AIDO1
SCHEMBL23780600 0.77 LMNA (0.33) SMN1; SMN2ALDH1A1
SCHEMBL23780604 0.74 LMNA (0.32)
SCHEMBL27882191 0.73 ALDH1A1 (0.43) SMN1; SMN2TSHRALDH1A1KMT2AIDO1
SCHEMBL23780596 0.71 TDP1 (0.36) TSHRALDH1A1CYP1A2CYP2C9
SCHEMBL23780598 0.70 ALDH1A1 (0.34) TSHRALDH1A1CYP3A4MAPK1
SCHEMBL23780591 0.70
SCHEMBL27936480 0.69 ALDH1A1 (0.47) SMN1; SMN2TSHRALDH1A1KMT2AMEN1
SCHEMBL945487 0.69 ALDH1A1 (0.47) SMN1; SMN2TSHRALDH1A1KMT2AIDO1
SCHEMBL23780588 0.69 NR4A1 (0.45) MAOBTSHRALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI SMN1; SMN2 4807/4885MAOB 229/4885CTSL 3931/4885
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI SMN1; SMN2 4807/4885MAOB 229/4885CTSL 3931/4885
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI SMN1; SMN2 4807/4885MAOB 229/4885CTSL 3931/4885
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI SMN1; SMN2 4807/4885MAOB 229/4885CTSL 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.