SCHEMBL23780588

SCHEMBL23780588

O=C(O)c1cccn1OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.45
NR4A2 P43354 1/20 0.45
NR4A3 Q92570 1/20 0.45
TSHR P16473 2/20 0.42
ALDH1A1 P00352 5/20 0.42
SRD5A2 P31213 2/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPK1 P28482 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
MEN1 O00255 1/20 0.40
PLA2G4B P0C869 1/20 0.40
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23798573 0.88 SRD5A2 (0.51) NR4A1NR4A2NR4A3SRD5A2
SCHEMBL23797927 0.85 RAB9A (0.52) ALDH1A1POLBPLA2G4B
SCHEMBL23799197 0.84 RAB9A (0.45) KMT2AMEN1PLA2G4BMAOB
SCHEMBL5510858 0.79 POLB (0.39) ALDH1A1LMNAL3MBTL1KMT2ATDP1
SCHEMBL23780602 0.79 L3MBTL1 (0.39) TSHRALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL7261337 0.76 HCAR2 (0.57) ALDH1A1LMNAL3MBTL1KMT2ATDP1
SCHEMBL6832383 0.76 LMNA (0.40) TSHRALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL2983076 0.73 ALDH1A1 (0.49) NR4A1NR4A2NR4A3TSHRALDH1A1
SCHEMBL23780589 0.73 TSHR (0.41) TSHRALDH1A1L3MBTL1KMT2ATDP1
SCHEMBL3110224 0.73 ADRA1D (0.47) TSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI NR4A1 2710/4885NR4A2 2799/4885NR4A3 2671/4885
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI NR4A1 2710/4885NR4A2 2799/4885NR4A3 2671/4885
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI NR4A1 2710/4885NR4A2 2799/4885NR4A3 2671/4885
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI NR4A1 2710/4885NR4A2 2799/4885NR4A3 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.