SCHEMBL237809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL236452	0.91	CNR1 (0.54)	TAAR1CNR1MLYCDMTORNPC1
	SCHEMBL3125988	0.86	MTOR (0.43)	TAAR1CNR1MLYCDMTORNPC1
	SCHEMBL3134457	0.83	POLB (0.49)	POLBALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL5073549	0.83	ALDH1A1 (0.53)	POLBALDH1A1SMN1; SMN2TAAR1CNR1
	SCHEMBL1794493	0.82	NPC1 (0.52)	POLBALDH1A1TAAR1CNR1NPC1
	SCHEMBL2549950	0.82	POLB (0.53)	POLBALDH1A1SMN1; SMN2CNR1MEN1
	SCHEMBL232868	0.82	MTOR (0.59)	MEN1KMT2AMLYCDMTORNPC1
	SCHEMBL6155598	0.82	POLB (0.71)	POLBALDH1A1SMN1; SMN2TAAR1CNR1
	SCHEMBL236381	0.80	HDAC6 (0.52)	POLBALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL3135827	0.80	POLB (0.56)	POLBALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.