SCHEMBL23784246

SCHEMBL23784246

C=C(C)C(=O)OCCOC(=O)C(=O)OC(C)C

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 4/20 0.53
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ADRA1A P35348 1/20 0.32
PDE4D Q08499 1/20 0.32
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18101452 0.85 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9161641 0.85 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3286289 0.85 THRB (0.71) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL20993683 0.85 TSHR (0.60) THRBTSHRALDH1A1ADRA1APDE4D
SCHEMBL31437420 0.85 TSHR (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL719781 0.85 TSHR (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15006942 0.83 THRB (0.63) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15636 0.82 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6142874 0.82 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2608279 0.82 THRB (0.49) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381370-A1 POLYMER PARTICLES TERUMO CORPORATION (JP) 2023-11-30 US disclosed
US-11759545-B2 Polymer particles TERUMO CORPORATION (JP) 2023-09-19 US disclosed
US-20210361823-A1 POLYMER PARTICLES TERUMO CORPORATION (JP) 2021-11-25 US disclosed
US-11110198-B2 Polymer particles TERUMO CORPORATION (JP) 2021-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210361823-A1 POLYMER PARTICLES FGB, PLG, PLAT THRB 4520/4885TSHR 2814/4885ALDH1A1 3057/4885
US-11759545-B2 Polymer particles FGB, PLG, PLAT THRB 4520/4885TSHR 2814/4885ALDH1A1 3057/4885
US-20230381370-A1 POLYMER PARTICLES FGB, PLG, PLAT THRB 4520/4885TSHR 2814/4885ALDH1A1 3057/4885
US-11110198-B2 Polymer particles FGB, PLG, PLAT THRB 4520/4885TSHR 2814/4885ALDH1A1 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.