Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689438 | 0.96 | PKM (0.35) | PKM | |
| SCHEMBL16681539 | 0.92 | RXRA (0.33) | PKM | |
| SCHEMBL23784651 | 0.88 | PIK3CA (0.34) | ORAI1 | |
| SCHEMBL16689414 | 0.86 | P2RX7 (0.33) | — | |
| SCHEMBL16688220 | 0.86 | PKM (0.38) | PKMMEN1KMT2AL3MBTL1 | |
| SCHEMBL16681375 | 0.85 | PDE3B (0.35) | — | |
| SCHEMBL16680952 | 0.85 | P2RX7 (0.32) | PKM | |
| SCHEMBL22135784 | 0.85 | RXRB (0.39) | PKMORAI1 | |
| SCHEMBL16680928 | 0.85 | RXRA (0.32) | — | |
| SCHEMBL23784627 | 0.84 | P2RX7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063144-B1 | ANTIPARASITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-08 | — | — | EP | disclosed |