SCHEMBL23786273

SCHEMBL23786273

CC(C)c1nc(Nc2ccncc2)nc(Nc2ccncc2)n1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 11/20 0.46
NFKB1 P19838 1/20 0.44
PDE4B Q07343 2/20 0.43
PDE4D Q08499 2/20 0.43
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 1/20 0.41
RAD52 P43351 1/20 0.39
ROCK1 Q13464 1/20 0.39
CHEK1 O14757 1/20 0.38
PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372514 0.83 KCNH3 (0.57) KCNH3NFKB1MAPTRAD52ROCK1
SCHEMBL23786202 0.82 KCNH3 (0.67) KCNH3NFKB1ALDH1A1MAPT
SCHEMBL23786279 0.80 KCNH3 (0.46) KCNH3ALDH1A1SMN1; SMN2MAPTRAD52
SCHEMBL23139658 0.78 KCNH3 (0.49) KCNH3ALDH1A1MAPTRAD52ROCK1
SCHEMBL23786257 0.77 KCNH3 (0.69) KCNH3PDE4BPDE4DALDH1A1SMN1; SMN2
SCHEMBL23786260 0.77 NPC1 (0.48) KCNH3NFKB1PDE4BPDE4DALDH1A1
SCHEMBL4544863 0.75 KCNH3 (0.70) KCNH3NFKB1ALDH1A1MAPTCHEK1
SCHEMBL23666307 0.75 NFKB1 (0.44) KCNH3NFKB1PDE4BPDE4DALDH1A1
SCHEMBL23666278 0.73 KCNH3 (0.45) KCNH3MAPTRAD52ROCK1CHEK1
SCHEMBL14071639 0.70 NFKB1 (0.63) KCNH3NFKB1PDE4BPDE4DSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220332970-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-10-20 US disclosed
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed