SCHEMBL23666307

SCHEMBL23666307

C=Cc1ccc(Nc2nc(Nc3ccc(C=C)cc3)nc(C(C)C)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.44
PDE4B Q07343 3/20 0.42
PDE4D Q08499 3/20 0.42
KCNH3 Q9ULD8 8/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786202 0.77 KCNH3 (0.67) NFKB1KCNH3ALDH1A1MEN1GAA
SCHEMBL23139075 0.77 NPC1 (0.39) KCNH3ALDH1A1SMN1; SMN2CA1CA2
SCHEMBL23786273 0.75 KCNH3 (0.46) NFKB1PDE4BPDE4DKCNH3ALDH1A1
SCHEMBL23786260 0.75 NPC1 (0.48) NFKB1PDE4BPDE4DKCNH3ALDH1A1
SCHEMBL23786257 0.75 KCNH3 (0.69) PDE4BPDE4DKCNH3ALDH1A1SMN1; SMN2
SCHEMBL11441071 0.74 NFKB1 (0.58) NFKB1SMN1; SMN2CA1CA2CA9
SCHEMBL30560616 0.73 TYR (0.47) NFKB1ALDH1A1SMN1; SMN2GAA
SCHEMBL23786275 0.71 EGFR (0.45) NFKB1PDE4BPDE4DKCNH3ALDH1A1
SCHEMBL11563830 0.71 ALDH1A1 (0.65) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL1697678 0.71 ALDH1A1 (0.65) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed
US-20210223436-A1 STRUCTURAL BODY, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-07-22 US disclosed