Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.44 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.44 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.43 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.40 |
| ▸ | MPL | P40238 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787725 | 0.85 | SENP2 (0.51) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787543 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787542 | 0.83 | SENP2 (0.44) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787534 | 0.83 | MEN1 (0.41) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787709 | 0.82 | APP (0.67) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787733 | 0.81 | ENPP2 (0.44) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787540 | 0.81 | APP (0.68) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787729 | 0.80 | APP (0.53) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787545 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL23787574 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MEN1THRBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | ACIBADEM MEHMET ALI AYDINLAR UNIVERSITESI (TR) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | POLG, POLB, POLA1 | ALDH1A1 3745/4885MEN1 2015/4885THRB 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.