Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.50 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.50 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.50 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787643 | 0.88 | PRMT3 (0.48) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787641 | 0.86 | SENP2 (0.66) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787582 | 0.83 | ENPP2 (0.42) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787776 | 0.83 | SENP2 (0.50) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787566 | 0.82 | SENP2 (0.49) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787580 | 0.82 | MEN1 (0.62) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787680 | 0.81 | SENP2 (0.54) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787772 | 0.81 | SENP2 (0.75) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787686 | 0.81 | SENP2 (0.61) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL23787548 | 0.80 | ENPP2 (0.48) | SENP2SENP1SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | ACIBADEM MEHMET ALI AYDINLAR UNIVERSITESI (TR) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | POLG, POLB, POLA1 | SENP2 1558/4885SENP1 1087/4885SUMO2 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.