Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468488 | 0.80 | AHR (0.61) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL1044390 | 0.76 | AHR (0.61) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL12427789 | 0.76 | AHR (0.61) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL154614 | 0.76 | AHR (1.00) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL152963 | 0.76 | AHR (0.61) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL433708 | 0.76 | AHR (0.61) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL19391 | 0.76 | AHR (0.67) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL5535534 | 0.76 | AHR (0.61) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL1459491 | 0.76 | TDP2 (0.62) | AHRPDE3BPDE3APDK2EPHX2 | |
| SCHEMBL6431 | 0.76 | AHR (0.72) | AHRPDE3BPDE3APDK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441389-B1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA INC (CN) | 2021-09-08 | — | — | EP | disclosed |