Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.61 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.58 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278958 | 0.84 | AHR (0.61) | AHRGRIA1CACNG8PKMEPHX2 | |
| SCHEMBL11927570 | 0.83 | HTR5A (0.52) | AHRGRIA1CACNG8PKMPDE3B | |
| SCHEMBL433753 | 0.82 | PKM (0.58) | PKMPDE3BPDE3AEPHX2CYP1A2 | |
| SCHEMBL29199433 | 0.82 | PKM (0.58) | PKMPDE3BPDE3AEPHX2CYP1A2 | |
| SCHEMBL10274620 | 0.82 | EPHX2 (0.55) | AHRGRIA1CACNG8PKMPDE3B | |
| SCHEMBL8263674 | 0.81 | PGR (0.68) | AHRGRIA1CACNG8PDE3BPDE3A | |
| SCHEMBL15601784 | 0.80 | PKM (0.48) | AHRGRIA1CACNG8PKMPDE3B | |
| SCHEMBL27859220 | 0.80 | PDE3B (0.64) | AHRGRIA1CACNG8PKMPDE3B | |
| SCHEMBL18189578 | 0.80 | GRIA1 (0.60) | AHRGRIA1CACNG8PKMPDE3B | |
| SCHEMBL10274553 | 0.79 | MAPT (0.53) | PKMEPHX2MMP12HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194833-B | Catalyst system for initiating lactide ring-opening polymerization and preparation method of polylactic acid | 中国科学技术大学 | 2020-10-27 | — | — | CN | claimed |
| US-20040067531-A1 | Methods of modulating protein tyrosine kinase function with substituted indolinone compounds | SUGEN, INC. | 2004-04-08 | — | — | US | claimed |
| US-20250171399-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY | 2025-05-29 | — | — | US | disclosed |
| WO-2025085819-A1 | KINASE INHIBITOR COMPOSITIONS AND RELATED METHODS FOR THE TREATMENT OF A DISEASE | WASHINGTON UNIVERSITY (US) | 2025-04-24 | — | — | WO | disclosed |
| US-20250042892-A1 | PREPARATION OF INDOLONE-3YL-HYDRAZONO-SUBSTITUTED 1,3-THIAZOLIDINONE DERIVATIVES AND APPLICATION THEREOF | UNIV FUDAN (CN) | 2025-02-06 | — | — | US | disclosed |
| CN-118974013-A | Pyrrolidine compounds | 伊莱利利公司 | 2024-11-15 | — | — | CN | disclosed |
| US-12030857-B2 | Glucose uptake inhibitors | KADMON CORPORATION, LLC (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3749355-B1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX KINASE (\"NACK\") AND METHODS FOR USE OF THE SAME | UNIV MIAMI (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2024112918-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| CN-114634501-B | 3, 5-Diaryl-thiazolidinone-azo chain-indolone derivative and preparation method and application thereof | 复旦大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114634503-B | Indole alkaloid heterocycle substituted-1, 3-thiazolidineone derivative and preparation method and application thereof | 复旦大学 | 2024-05-24 | — | — | CN | disclosed |
| EP-0164860-A1 | N,3-disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents | PFIZER INC. (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4556672-A | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents | PFIZER INC. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0156603-A2 | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents | PFIZER INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0155828-A2 | Process for making 2-oxindole-1-carboxamides and intermediates therefor | PFIZER INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0153818-A2 | 1,3-Disubstituted 2-oxindoles as analgesic and anti-inflammatory agents | PFIZER INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-RE29882-E | SALT FORMATION, REARRANGEMENT, DESULFURIZATION | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4056569-A | Ortho-[(alkylthio)(aminocarbonyl)methyl]anilines | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-3996264-A | Synthesis of oxindoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-12-07 | — | — | US | disclosed |
| US-3972894-A | Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030857-B2 | Glucose uptake inhibitors | SLC2A1, SLC2A4, SLC2A2 | AHR 1448/4885GRIA1 300/4885CACNG8 4365/4885 |
| US-20040067531-A1 | Methods of modulating protein tyrosine kinase function with substituted indolinone compounds | ABL1, LCK, PNCK | AHR 1643/4885GRIA1 1170/4885CACNG8 3399/4885 |
| US-20250171399-A1 | PYRROLIDINE COMPOUNDS | SDHA, GMPS, SDHB | AHR 2982/4885GRIA1 3809/4885CACNG8 3277/4885 |
| US-20250042892-A1 | PREPARATION OF INDOLONE-3YL-HYDRAZONO-SUBSTITUTED 1,3-THIAZOLIDINONE DERIVATIVES AND APPLICATION THEREOF | PARP14, PARP4, PARP11 | AHR 2635/4885GRIA1 1883/4885CACNG8 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.