Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.67 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL9732811 | 0.98 | AHR (0.65) | AHRPDE3BPDE3APGRPDK2 | |
| SCHEMBL31478025 | 0.84 | AHR (0.61) | AHRPDE3BPDE3APDK2MAOB | |
| SCHEMBL1833499 | 0.84 | AHR (0.61) | AHRPDE3BPDE3APDK2MAOB | |
| SCHEMBL426336 | 0.82 | NPC1 (0.55) | AHRPDE3BPDE3AMAOBMAOA | |
| SCHEMBL26768740 | 0.82 | TDP2 (0.51) | AHRPDK2MAOBMAOACMA1 | |
| SCHEMBL29853427 | 0.82 | TDP2 (0.51) | AHRPDK2MAOBMAOACMA1 | |
| SCHEMBL31734649 | 0.82 | MAOA (0.55) | AHRPDE3BPDE3APDK2MAOB | |
| SCHEMBL5639130 | 0.81 | AHR (0.50) | AHRPDE3BPDE3APGRPDK2 | |
| SCHEMBL154614 | 0.80 | AHR (1.00) | AHRPDE3BPDE3APGRPDK2 | |
| SCHEMBL6405990 | 0.79 | MAPT (0.58) | AHRMAOBMAOADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116585307-B | Application of 5-hydroxy oxindole in preparation of medicines for treating acute respiratory distress syndrome | 重庆医科大学 | 2024-08-20 | — | — | CN | claimed |
| CN-116585307-A | Application of 5-hydroxy oxindole in preparation of medicines for treating acute respiratory distress syndrome | 重庆医科大学 | 2023-08-15 | — | — | CN | claimed |
| CN-111208230-B | Method for detecting American cockroach intestinal flora metabolite | 天津中医药大学 | 2022-02-25 | — | — | CN | claimed |
| US-20220016099-A1 | BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF | TRINUERO (KR) | 2022-01-20 | — | — | US | claimed |
| CN-109942480-B | Synthetic method of aromatic ring indole-5-alcohol compound | 河南师范大学 | 2021-09-10 | — | — | CN | claimed |
| WO-2020116742-A1 | BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF | 주식회사 트리뉴로 | 2020-06-11 | — | — | WO | claimed |
| CN-111208230-A | Method for detecting American cockroach intestinal flora metabolite | 天津中医药大学 | 2020-05-29 | — | — | CN | claimed |
| WO-2001078722-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 5-HYDROXYOXINDOLE AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-10-25 | — | — | WO | claimed |
| EP-4720316-A2 | NON-VIRAL CELL ENGINEERING | Arsenal Biosciences, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2025097170-A1 | A METHOD OF MINIMIZING OR ELIMINATING NEPHROTOXICITY IN PATIENTS UNDERGOING TREATMENT WITH ANTIMICROBIAL OR ANTICANCER DRUGS | PROLETARIAT THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025093926-A1 | A METHOD OF MINIMIZING OR ELIMINATING NEPHROTOXICITY IN PATIENTS UNDERGOING CISPLATIN-BASED CHEMOTHERAPY VIA SEQUENTIAL ADMINISTRATION OF A PROTECTIVE AGENT FOLLOWED BY A TOXIC AGENT | AKIHIKO SAITO (JP) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025064829-A1 | A MOLECULAR SCAFFOLD FOR DEPLETING HRPN13 AND A SELECT GROUP OF KEN BOX PROTEINS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2024259376-A2 | NON-VIRAL CELL ENGINEERING | ARSENAL BIOSCIENCES, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| US-4629733-A | CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1986-12-16 | — | — | US | disclosed |
| EP-0170117-A1 | Oxindole derivatives, process for their preparation, pharmaceutical compositions containing them and intermediate compounds | Roche Diagnostics GmbH (DE) | 1986-02-05 | — | — | EP | disclosed |
| EP-0026474-B1 | COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR | Wella Aktiengesellschaft (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | disclosed |
| US-4329347-A | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016099-A1 | BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF | KEAP1, SLC5A1, GCLC | AHR 1552/4885PDE3B 1882/4885PDE3A 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.