Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25846123 | 0.86 | TDP1 (0.54) | TDP1L3MBTL1FAAHCNR1CNR2 | |
| SCHEMBL21844332 | 0.82 | CHRNB2 (0.46) | TDP1L3MBTL1CHRNB2CHRNA4CYP2D6 | |
| SCHEMBL10172770 | 0.76 | CHRNB2 (0.48) | TDP1L3MBTL1CHRNB2CHRNA4CYP2D6 | |
| SCHEMBL22430399 | 0.75 | TDP1 (0.58) | TDP1L3MBTL1FAAHCNR1CNR2 | |
| SCHEMBL15677593 | 0.73 | CHRNB2 (0.46) | TDP1L3MBTL1CHRNB2CHRNA4CYP2D6 | |
| SCHEMBL26806573 | 0.73 | CYP1A2 (0.47) | TDP1L3MBTL1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL28856610 | 0.73 | L3MBTL1 (0.60) | TDP1L3MBTL1FAAHTLR8TLR7 | |
| SCHEMBL13610217 | 0.73 | L3MBTL1 (0.60) | TDP1L3MBTL1FAAHTLR8TLR7 | |
| SCHEMBL20366346 | 0.72 | TDP1 (0.59) | TDP1L3MBTL1FAAHCNR1CNR2 | |
| SCHEMBL23934127 | 0.72 | CNR1 (0.45) | TDP1L3MBTL1FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275563-A1 | HIGHLY ACTIVE COMPOUNDS AGAINST COVID-19 | Atea Pharmaceuticals, Inc. (US) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275563-A1 | HIGHLY ACTIVE COMPOUNDS AGAINST COVID-19 | PNP, MTAP, ACE2 | TDP1 753/4885L3MBTL1 2523/4885FAAH 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.