Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 6/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372004 | 0.86 | DUT (0.35) | PKMDUTCRBN | |
| SCHEMBL18661677 | 0.86 | DUT (0.35) | PKMDUTCRBN | |
| SCHEMBL22580343 | 0.82 | P2RY2 (0.43) | — | |
| SCHEMBL22889224 | 0.82 | DUT (0.33) | DUT | |
| SCHEMBL22580878 | 0.77 | DUT (0.32) | DUT | |
| SCHEMBL16566363 | 0.75 | PKM (0.36) | PKMDUTCRBN | |
| SCHEMBL24371968 | 0.74 | P2RY2 (0.31) | — | |
| SCHEMBL22837315 | 0.74 | CYP3A4 (0.33) | DUT | |
| SCHEMBL12031271 | 0.72 | DUT (0.36) | PKMDUTCRBN | |
| SCHEMBL19881999 | 0.72 | DUT (0.36) | PKMDUTCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275563-A1 | HIGHLY ACTIVE COMPOUNDS AGAINST COVID-19 | Atea Pharmaceuticals, Inc. (US) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275563-A1 | HIGHLY ACTIVE COMPOUNDS AGAINST COVID-19 | PNP, MTAP, ACE2 | PKM 2218/4885DUT 29/4885CRBN 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.