Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15033453 | 0.80 | ATM (0.58) | TP53ATMHPGDALDH1A1MAPT | |
| SCHEMBL24529 | 0.79 | TP53 (0.55) | TP53ATMHPGDALDH1A1MAPT | |
| SCHEMBL19275967 | 0.74 | MAPK1 (0.72) | TP53ATMHPGDALDH1A1HSD17B10 | |
| SCHEMBL15020819 | 0.72 | HPGD (0.82) | TP53ATMHPGDALDH1A1MAPT | |
| SCHEMBL25411 | 0.71 | HSD17B10 (0.80) | TP53ATMHPGDALDH1A1MAPT | |
| SCHEMBL24528 | 0.70 | TP53 (0.54) | TP53ATMHPGDALDH1A1MAPT | |
| SCHEMBL1104823 | 0.70 | ALDH1A1 (0.71) | ATMALDH1A1HSD17B10THRBHTT | |
| SCHEMBL31451 | 0.68 | ATM (0.67) | TP53ATMHPGDALDH1A1MAPT | |
| SCHEMBL19275966 | 0.67 | MAPK1 (0.64) | TP53ATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL19142835 | 0.67 | MAPK1 (0.47) | TP53ATMALDH1A1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026766-A2 | NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME | (주)네오팜 (KR) | 2012-03-01 | — | — | WO | disclosed |