Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15033453 | 0.83 | ATM (0.58) | TP53HPGDALDH1A1ATMMAPT | |
| SCHEMBL15020819 | 0.80 | HPGD (0.82) | TP53HPGDALDH1A1ATMMAPT | |
| SCHEMBL3307690 | 0.80 | ADRB1 (0.67) | TP53HPGDALDH1A1MAPTADRB1 | |
| SCHEMBL17281442 | 0.80 | ADRB1 (0.67) | TP53HPGDALDH1A1MAPTADRB1 | |
| SCHEMBL23791 | 0.79 | TP53 (0.53) | TP53HPGDALDH1A1ATMMAPT | |
| Hydrochloric Acid SCHEMBL1803475 | 0.78 | ADRB1 (0.65) | TP53HPGDALDH1A1MAPTADRB1 | |
| SCHEMBL12991 | 0.78 | ADRB1 (0.69) | TP53HPGDALDH1A1MAPTADRB1 | |
| SCHEMBL19275967 | 0.77 | MAPK1 (0.72) | TP53HPGDALDH1A1ATMKDM4E | |
| SCHEMBL8264176 | 0.74 | ADRB1 (0.69) | HPGDALDH1A1MAPTADRB1KDM4E | |
| SCHEMBL25411 | 0.74 | HSD17B10 (0.80) | TP53HPGDALDH1A1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610255-B1 | 1H-Benzo[d]imidazol-5-yl compounds and composition for treating inflammatory diseases | NEOPHARM CO LTD (KR) | 2016-02-24 | — | — | EP | disclosed |
| EP-2610255-A2 | NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME | Neopharm Co., Ltd. (KR) | 2013-07-03 | — | — | EP | disclosed |