Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15033453 | 0.76 | ATM (0.58) | TP53ATMALDH1A1HPGDMAPT | |
| SCHEMBL6558765 | 0.75 | HTR2C (0.45) | HPGDMAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL24529 | 0.72 | TP53 (0.55) | TP53ATMALDH1A1HPGDMAPT | |
| SCHEMBL19275967 | 0.71 | MAPK1 (0.72) | TP53ATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL3169257 | 0.70 | HTR2C (0.46) | MAPTLMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL23791 | 0.70 | TP53 (0.53) | TP53ATMALDH1A1HPGDMAPT | |
| SCHEMBL25411 | 0.68 | HSD17B10 (0.80) | TP53ATMALDH1A1HPGDMAPT | |
| SCHEMBL15020819 | 0.67 | HPGD (0.82) | TP53ATMALDH1A1HPGDMAPT | |
| SCHEMBL1104823 | 0.66 | ALDH1A1 (0.71) | ATMALDH1A1THRBHSD17B10HTT | |
| SCHEMBL3153900 | 0.66 | ALDH1A1 (0.37) | TP53ATMALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610255-B1 | 1H-Benzo[d]imidazol-5-yl compounds and composition for treating inflammatory diseases | NEOPHARM CO LTD (KR) | 2016-02-24 | — | — | EP | disclosed |
| EP-2610255-A2 | NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME | Neopharm Co., Ltd. (KR) | 2013-07-03 | — | — | EP | disclosed |