Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23791268 | 0.86 | GPR119 (0.48) | CYP11B2RORCACACBSCD5GPR119 | |
| SCHEMBL23791307 | 0.85 | CYP11B2 (0.43) | CYP11B2PIK3R1PIK3CAHDAC2RORC | |
| SCHEMBL2427136 | 0.82 | RORC (0.44) | CYP11B2HDAC2RORCHDAC1ACACB | |
| SCHEMBL31283570 | 0.80 | SYK (0.42) | CYP11B2PIK3R1PIK3CARORCACACB | |
| SCHEMBL2283209 | 0.80 | CYP11B2 (0.45) | CYP11B2HDAC2RORCHDAC1ACACB | |
| SCHEMBL3545555 | 0.80 | RORC (0.54) | HDAC2RORCHDAC1 | |
| SCHEMBL18149524 | 0.80 | GPR119 (0.41) | CYP11B2ACACBGPR119SYK | |
| SCHEMBL7470277 | 0.79 | GPR119 (0.46) | CYP11B2SCD5GPR119USP30 | |
| SCHEMBL23742297 | 0.78 | CYP11B2 (0.56) | CYP11B2PIK3R1PIK3CAHDAC2HDAC1 | |
| SCHEMBL23791313 | 0.78 | SYK (0.44) | CYP11B2PIK3R1PIK3CARORCACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210276978-A1 | INHIBITORS OF HISTONE DEACETYLASE | ALKERMES, INC. | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276978-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC7 | CYP11B2 841/4885PIK3R1 2062/4885PIK3CA 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.