SCHEMBL237922

SCHEMBL237922

N#Cc1ccc(N)c(N)c1C#N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
USP2 O75604 1/20 0.35
MAPKAPK2 P49137 4/20 0.33
GAA P10253 3/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 2/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30352793 1.00 KDM4E (0.35) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL10734596 0.83 KDM4E (0.36) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL5952373 0.80 KDM4E (0.38) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL2428317 0.77 GRM6 (0.41) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL10692318 0.77 CYP1A2 (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL31399295 0.76 TSHR (0.39) KDM4EALDH1A1CYP3A4USP2GAA
SCHEMBL152358 0.76 TSHR (0.39) KDM4EALDH1A1CYP3A4USP2GAA
SCHEMBL15365364 0.74 KDM4E (0.38) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL30432017 0.74 TRPV4 (0.38) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL22684010 0.74 TRPV4 (0.38) KDM4EALDH1A1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081861-A Multiple resonance organic dye and preparation method and application thereof 上海大学 2025-06-03 CN claimed
CN-116217500-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2025-05-16 CN claimed
CN-119431777-A Biological multi-functional group active nitrile resin and solvent-free green synthesis method thereof 成都大学 2025-02-14 CN claimed
CN-118324701-A Photosensitive nano prodrug for photodynamic-immune cooperative treatment of tumor as well as preparation method and application thereof 西安交通大学 2024-07-12 CN claimed
CN-118325281-A Flame-retardant high polymer material for aerospace equipment and preparation method thereof 东莞市卡帝德塑化科技有限公司 2024-07-12 CN claimed
CN-116217500-A Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2023-06-06 CN claimed
CN-120081861-A Multiple resonance organic dye and preparation method and application thereof 上海大学 2025-06-03 CN disclosed
CN-116217500-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2025-05-16 CN disclosed
CN-119431777-A Biological multi-functional group active nitrile resin and solvent-free green synthesis method thereof 成都大学 2025-02-14 CN disclosed
CN-115558135-B High heat-resistant polyimide film with cross-linked structure, preparation method and application 大连理工大学 2024-10-08 CN disclosed
CN-118324701-A Photosensitive nano prodrug for photodynamic-immune cooperative treatment of tumor as well as preparation method and application thereof 西安交通大学 2024-07-12 CN disclosed
CN-118325281-A Flame-retardant high polymer material for aerospace equipment and preparation method thereof 东莞市卡帝德塑化科技有限公司 2024-07-12 CN disclosed
CN-118325281-A Flame-retardant high polymer material for aerospace equipment and preparation method thereof 东莞市卡帝德塑化科技有限公司 2024-07-12 CN disclosed
US-20120101243-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM UNITED STATES DEPARTMENT OF ENERGY 2012-04-26 US disclosed
CN-101514262-B Ethylene naphthalene and paradiazine dye and application thereof to dye-sensitized solar cells. UNIV DALIAN TECH 2012-04-25 CN disclosed
US-8106393-B2 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-31 US disclosed
US-20120004384-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM UNITED STATES DEPARTMENT OF ENERGY 2012-01-05 US disclosed
US-7919770-B2 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom NORTH CAROLINA STATE UNIVERSITY (US) 2011-04-05 US disclosed
US-20110015388-A1 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom UNITED STATES DEPARTMENT OF ENERGY 2011-01-20 US disclosed
CN-101514262-A Ethylene naphthalene and paradiazine dye and application thereof to dye-sensitized solar cells. UNIV DALIAN TECH (CN) 2009-08-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004384-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM PNMT, HNMT, COMT KDM4E 1521/4885ALDH1A1 767/4885CYP1A2 206/4885
US-20120101243-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM PNMT, HNMT, COMT KDM4E 1521/4885ALDH1A1 767/4885CYP1A2 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.