Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15086054 | 0.79 | MAOA (0.50) | MAOAMAOBTSHR | |
| SCHEMBL2016516 | 0.79 | TSHR (0.47) | HPGDMAOAMAOBTSHRHDAC3 | |
| SCHEMBL4109066 | 0.78 | KMO (0.65) | HPGDKMOTSHRHDAC3HDAC4 | |
| SCHEMBL16795752 | 0.76 | TSHR (0.48) | HPGDKMOMAOAMAOBTSHR | |
| SCHEMBL20619804 | 0.76 | MAOA (0.44) | HPGDMAOAMAOBTSHRHDAC3 | |
| SCHEMBL17411406 | 0.75 | TSHR (0.47) | HPGDKMOMAOAMAOBTSHR | |
| SCHEMBL5165126 | 0.75 | HTT (0.45) | HPGD | |
| SCHEMBL21294933 | 0.75 | TSHR (0.47) | HPGDKMOMAOAMAOBTSHR | |
| SCHEMBL2019475 | 0.75 | TSHR (0.47) | HPGDGRNSORT1KMOTSHR | |
| SCHEMBL990763 | 0.75 | TSHR (0.47) | HPGDKMOMAOAMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |