Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079129 | 1.00 | TSHR (0.32) | TSHRTDP1LMNANPSR1GAA | |
| SCHEMBL23940856 | 0.87 | TSHR (0.30) | TSHR | |
| SCHEMBL24088583 | 0.82 | LMNA (0.50) | TSHRTDP1LMNANPSR1GAA | |
| SCHEMBL19890880 | 0.82 | LMNA (0.50) | TSHRTDP1LMNANPSR1GAA | |
| SCHEMBL24165329 | 0.82 | LMNA (0.50) | TSHRTDP1LMNANPSR1GAA | |
| SCHEMBL25125051 | 0.77 | — | — | |
| SCHEMBL23793813 | 0.77 | — | — | |
| SCHEMBL23793923 | 0.77 | — | — | |
| SCHEMBL18853767 | 0.74 | LMNA (0.36) | TSHRTDP1LMNANPSR1GAA | |
| SCHEMBL17066960 | 0.71 | LMNA (0.36) | TSHRTDP1LMNANPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253366-A2 | METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION | Gilead Sciences, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| WO-2021176366-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2021-09-10 | — | — | WO | disclosed |